Biologia Parasitária - IOC

Programa de pós-graduação stricto sensu em biologia parasitária

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Profile and Contacts


Check out the listing of the faculty of Post-Graduate program in Parasite Biology of Instituto Oswaldo Cruz (IOC/Fiocruz). The listing is separated by Area of concentration in which the faculty is inserted.

 

Permanent faculty of the program
Area of Concentration in Biology

 

Supervisor

E-mail

Curriculum

Research interests

Arnaldo Maldonado Junior

maldonad@ioc.fiocruz.br

CV

1 - In vitro models of trematodes to assess the efficacy and safety profile of novel drug candidates: natural and synthetic anti-helminth compounds. 2 –Taxonomy and molecular systematic analysis of helminths.

Claudia Magalhães Calvet

cmcalvet@ioc.fiocruz.br

CV

Mechanisms of extracellular matrix regulation during the interaction of Trypanosoma cruzi-host cells and drug development for Chagas disease 

Cláudia Portes Santos Silva

cpsantos@ioc.fiocruz.br

CV

Biological and taxonomic aspects of human and veterinary helminths: ultrastructure analysis, experimental evolutive cycles, molecular biology, and altered host’s behavior due to the parasitism; control of parasite load.

Helene Santos Barbosa

helene@ioc.ficoruz.br

CV

Studies related to the cellular and molecular aspects involved during the interaction of Toxoplasma gondii and mammalian skeletal muscle cells (lytic cycle, cytogenesis and congenital transmission) and with feline enterocytes (sexual cycle).

Marcos André Vannier dos Santos

marcos.vannier@ioc.fiocruz.br

CV

Bioassays of antiparasitic compounds using the ultrastructural evaluation, in order to elucidate the mechanisms of action from alterations of the subcellular architecture. Combined therapies using repositioned drugs, natural, synthetic and semisynthetic products are tested for synergistic associations, particularly the oxidative stress selectively generated in parasitic protozoa. In addition to experimental activities, the team acts in the popularization of sciences, especially in relation to parasitic diseases for health promotion                                                                            www.Oe1oQornHCaoX8aafug

Margareth Maria de Carvalho Queiroz

mmcqueiroz@ioc.fiocruz.br

CV

Binary, morphology, taxonomy of Diptera Muscomorpha, forensic entomology and alternative control of insects (dipteres, muscoides and triatomines) of sanitary relevance.

Maria de Nazaré Correia Soeiro

soeiro@ioc.fiocruz.br

CV

(i)Immune-biological aspects involved in the parasite-hosts interaction, (ii) novel experimental therapeutic strategies (in silico, in vitro and in vivo) for drug development towards tropical neglected diseases caused by trypanosomatid parasites such as T.cruzi and Leishmania, and (iii) new approaches for drug development of anti-inflammatory and antitumor agents..

Mirian Claudia de Souza Pereira

mirian@ioc.fiocruz.br

CV

Development of research projects related to experimental Chagas disease focusing on the biological aspects of parasite-host cell interaction aiming to contribute for the knowledge of the cellular recognition mechanisms and signaling pathways involved in the parasite invasion process.

Rubem Figueiredo Sadok Menna Barreto

rubemb@ioc.fiocruz.br

CV

In vitro e in vivo analysis of the drug effect upon different protozoan pathogenic parasites, also characterizing their modes of action. Analysis of the autophagy process, mitochondrial metabolism and oxidative state of parasites and hosts during the disease outcome, reporting related cellular and molecular mechanisms.

 

 

 

 

 

 

 

 

 

 

 

 

 

     

 

 

Permanent faculty of the program
Area of Concentration in Genetics and Biochemistry

Supervisor

E-mail

Curriculum

Research interests

Ademir de Jesus Martins Junior

ademirjr@ioc.fiocruz.br

CV

Genetic basis of insecticide resistance and its effects on fitness in insects of sanitary importance.

Ana Carolina Paulo Vicente

anapaulo@ioc.fiocruz.br

CV

Molecular Genetics of microorganisms - bacteria in the themes: diversity, taxonomy, virulence / resistance to antimicrobials, genomics and metagenomics.

Carlos Roberto Alves

calves@ioc.fiocruz.br

CV

Biochemistry of protozoan parasites, with emphasis on proteins and proteases, and their actions on the physiology of pathogenic protozoa, such as Leishmania sp and Trypanosoma cruzi. The research group has focused on relevant structural problems of interaction of supramolecular complexes (MHC-peptide, antigen-antibody, enzyme-inhibitor, receptor-ligand, protein-DNA, DNA-DNA, RNA-RNA etc.) in typical biological problems of the interaction between parasite and host that aims the development of vaccines, drugs and immunodiagnosis.

Constança Felicia de Paoli de Carvalho Britto

cbritto@ioc.fiocruz.br

CV

Molecular diagnosis and ecoepidemiology of leishmaniasis and Chagas' disease. To evaluate natural infection and vector competence in vector insects and, to monitor therapeutic efficacy in patients affected by Trypanosoma cruzi infection.

Denise Valle

dvalle@ioc.fiocruz.br

CV

Physiology and vector control, focusing on culicide and especially on Aedes aegypti; Resistance to insecticides, mechanisms of resistance, the relationship between resistance and aspects of viability; Nature and molecular basis of egg resistance of culicide desiccation; Vector control alternatives, including products, strategies and pipelines.

Elisa Cupolillo

elisa.cupolillo@ioc.fiocruz.br

CV

Molecular systematics applied to leishmaniasis, including the development and application of molecular markers in the specific diagnosis of Leishmania. In addition, addressing the issue of population genetics of leishmaniasis and phlebotomine neotropical vectors, aiming to: (i) elucidate the nature and dynamics of specific cycles of parasite transmission in different ecological niches; (ii) understanding of clinical pleomorphism and phenotypic diversity (in vivo and in vitro) and (iii) understanding the evolution of the parasite.

Elmo Eduardo de Almeida Amaral

elmo@ioc.fiocruz.br

CV

In vitro and in vivo activity of bioactive compounds in Leishmania spp sensitive and resistant to Antimony, with a definition of the mechanism of action, pharmacokinetic study and toxicity. Effect of the combination of reference drugs for the treatment of leishmaniasis with natural compounds; Importance of antioxidant enzymes of Leishmania spp with emphasis on virulence and infectivity; Role of Protein Kinase C in Cellular Physiology of Leishmania spp.

Fernando Araujo Monteiro

fam@ioc.fiocruz.br

CV

1. Molecular Systematics and Phylogeography of Chagas disease vectors based on mitochondrial and nuclear markers. 2. Genetics of populations and structuring of triatomines based on microsatellite markers. 3. DNA barcoding of parasites and vectors of Brazil. 4. Triatomine microbiota evaluation based on new generation DNA sequencing techniques (NGS).

Flavia Barreto dos Santos

flaviab@ioc.fiocruz.br

CV

Laboratory diagnosis, in vitro and in vivo studies and molecular epidemiology of Dengue Virus. Stabi Establish molecular methods for the diagnosis and molecular epidemiology of Chikungunya virus.

Márcio Lourenço Rodrigues

marciolr@cdts.fiocruz.br

CV

Development of tools with potential application in the prevention or control of human diseases caused by fungi.

Marize Pereira Miagostovich

marizepm@ioc.fiocruz.br

CV

Environmental and Food Virology.

Monick Lindenmeyer Guimarães

monicklg@ioc.fiocruz.br

CV

Molecular biology, virology, and immunology, with emphasis on the molecular diversity of HIV and its implications on pathogenesis.

Natalia Motta Araujo

nmaraujo@ioc.fiocruz.br

CV

Studies of hepatitis B and C viruses with emphasis on the following topics: molecular epidemiology, phylogeography, analysis of quasispecies in biological fluids, viral, genetic and epigenetic biomarkers for liver cancer.

Permanent faculty of the program
Area of Concentration in E
cology and Epidemiology

Supervisor

E-mail

Curriculum

Research interests

Alda Maria da Cruz

alda@ioc.fiocruz.br

CV

Pathogenesis of Infectious and Parasitic Diseases                                                                   Development of Methods for Diagnosis and Control of Infectious and Parasitic Diseases

Cláudio Tadeu Daniel Ribeiro

ribeiro@ioc.fiocruz.br

CV

Experience in Parasitology area, with emphasis on Human Protozoology, acting mainly on the following subjects: human and experimental malaria (simian and mice), Plasmodium falciparum and P. vivax, protective immunity, vaccine trials and malaria immunopathology. Also of interest are the history of immunology and cognitive aspects of immune and neural responses

Danuza de Almeida Esquenazi

esquenazi.danuza@gmail.com

CV

Investigation of the pathogenesis and regulation of the cellular immune response of leprosy per se and its reactional forms; Research on human aging, with emphasis on immunosenescence mechanisms

Edson Elias da Silva

edson@ioc.fiocruz.br

CV

Virology, Enterovirus and Poliovirus; Study of viral agents involved in syndromes of the central nervous system

Elzinandes Leal de Azevedo

elzinandesazevedo@fiocruz.br

 

Immune response of host to infection by arboviruses of medical importance Dengue, Zika and Chikungunha. Emphasis: Natural killer cells, pattern recognition receptors, regulatory T cells and co-infection with HIV.

Euzenir Nunes Sarno

euzenir@ioc.fiocruz.br

CV

Clinical, epidemiological, immunological and molecular studies of leprosy.

Fátima da Conceição Silva

fconcei@ioc.fiocruz.br

CV

Parasitic diseases in humans and animals: immunology, diagnosis, clinical and treatment, with emphasis on those caused by parasites of the genus Leishmania; Mycoses in humans and animals: clinical, pathogenesis, immunology, diagnosis and treatment with emphasis on sporotrichosis; other fungal diseases;          Characterization and determination of the influence of the systemic and in situ immune response on the evolution of infectious and parasitic diseases of the cutaneous mucosal integument, skin immunity, in situ studies, inflammation, immunohistochemistry and murine models.

José Paulo Gagliardi Leite

jpgleite@ioc.fiocruz.br

CV

Detection and molecular characterization of viruses responsible for the etiology of acute gastroenteritis and development of diagnostic methodologies.

Joseli de Oliveira Ferreira

lila@ioc.fiocruz.br

CV

Study of the natural immunity to antigens candidates to compose an antimalarial vaccine, the genetic control of antiplasmodial specific immune response and immunopathology in human malaria in populations of Brazilian endemic areas.

Joseli Lannes Vieira

lannes@ioc.fiocruz.br

CV

Development of vaccines against parasitic infections; Immunopathogenesis and immunoregulation in parasitic infections.

Josué da Costa Lima Júnior

josue@ioc.fiocruz.br

CV

Development and evaluation of synthetic and recombinant antigens based on potentially vaccine proteins against malaria: Antigenicity, Immunogenicity and associations with the HLA of populations living in endemic areas.

Katia da Silva Calabrese

calabrese@ioc.fiocruz.br

CV

Research with protozoan parasites of macrophages in an experimental model including: immunology and therapeutics of leishmaniasis; pathology and immunology of Chagas' disease, emphasis on oral infection; ocular and intestinal toxoplasmosis.

Leonardo José Moura de Carvalho

leojmc@ioc.fiocruz.br

CV

Role of vascular dysfunction and inflammation in the pathogenesis and therapeutics of cerebral malaria, new drugs against hepatic and erythrocytic forms of Plasmodium falciparum and P. vivax, Vaccines against malaria.

Lilian Rose Pratt Riccio

riccio@ioc.fiocruz.br

CV

Study of the cellular and humoral immune responses against Plasmodium falciparum antigens and Plasmodium vivax canidatos the antimalarial vaccine in naturally exposed populations living in the Brazilian Amazon and evaluation of the role of human and parasite polymorphisms in the development of the specific immune response. In vitro evaluation of the resistance of Plasmodium falciparum and Plasmodium vivax isolates to antimalarial drugs and the evaluation of the antimalarial potential of new drugs of established or experimental use.

Luzia Maria de Oliveira

lpinto@ioc.fiocruz.br

CV

Mechanisms of deregulation of host immune response in Dengue infection, observing the involvement of components of the Complement System, Chemokines and proteins associated with coagulation and inflammation.

Marcelo Alves Pinto

marcelop@ioc.fiocruz.br

CV

Pathogenesis of acute viral hepatitis and non-human primate fulminants as models for the study of the pathogenesis of viral hepatitis study of hepatitis by hepatitis A virus, hepatitis E, HSV1 and 2, and parvovirus B19 Balb C mouse as an experimental model for herpetic encephalitis targeted for selection of new antiviral drugs and interference RNA therapy.

Maria de Fátima Ferreira da Cruz

mffcruz@ioc.fiocruz.br

CV

Malaria: Diagnosis, chemoresistance, gene polymorphism and immunopathology.

Mariza Gonçalves Morgado

mmorgado@ioc.fiocruz.br

CV

Our main interests concern: HIV diversity and its implications for progression to AIDS, epitopes of interest in vaccines, drug resistance and viral evolution. Immunopathology of HIV infection and HIV-Tuberculosis interaction.

Myrna Cristina Bonaldo

myrna.bonaldo@gmail.com

CV

Establishment of yellow fever vaccine virus as an expression platform for recombinant vaccines targeting human pathogens and understanding the structure and function of the viral genome.

Patricia de Azambuja Penna

azambuja.p@gmail.com

CV

Aspects of the interaction of triatomines with the parasite Trypanosoma cruzi, an etiological agent of Chagas' disease: in this line of research, the digestion physiology, intestinal microbiota, endocrinology and insect immunology, especially Rhodnius prolixus, are analyzed.

Roberta Olmo Pinheiro

rolmo@ioc.fiocruz.br

CV

IHost-pathogen interaction, cell death (apoptosis, pyroptose and autophagy), phagocytosis, immunoregulation, and inflammation. I have studied the immunopathogenic mechanisms related to the different clinical forms of leprosy, as well as to the reactional episodes of the disease. 

Vanessa Salete de Paula

vdepaula@ioc.fiocruz.br

CV

Viral hepatitis with emphasis on molecular epidemiology, genotyping, development and optimization of molecular diagnostic methods, serological and alternative methods of collection. It also works with herpes viruses, mainly with differential diagnosis, molecular epidemiology, co-infection with HIV and antiviral RNA interference therapy (RNAi).

Permanent faculty of the program
Area of Concentration in Genetics and Biochemistry in Immunology and Pathogenesis

Supervisor

E-mail

Curriculum

Research interests

Alda Maria da Cruz

alda@ioc.fiocruz.br

CV

Pathogenesis of Infectious and Parasitic Diseases                                                                   Development of Methods for Diagnosis and Control of Infectious and Parasitic Diseases

Cláudio Tadeu Daniel Ribeiro

ribeiro@ioc.fiocruz.br

CV

Experience in Parasitology area, with emphasis on Human Protozoology, acting mainly on the following subjects: human and experimental malaria (simian and mice), Plasmodium falciparum and P. vivax, protective immunity, vaccine trials and malaria immunopathology. Also of interest are the history of immunology and cognitive aspects of immune and neural responses

Danuza de Almeida Esquenazi

esquenazi.danuza@gmail.com

CV

Investigation of the pathogenesis and regulation of the cellular immune response of leprosy per se and its reactional forms; Research on human aging, with emphasis on immunosenescence mechanisms

Edson Elias da Silva

edson@ioc.fiocruz.br

CV

Virology, Enterovirus and Poliovirus; Study of viral agents involved in syndromes of the central nervous system

Elzinandes Leal de Azevedo

elzinandesazevedo@fiocruz.br

 

Immune response of host to infection by arboviruses of medical importance Dengue, Zika and Chikungunha. Emphasis: Natural killer cells, pattern recognition receptors, regulatory T cells and co-infection with HIV.

Euzenir Nunes Sarno

euzenir@ioc.fiocruz.br

CV

Clinical, epidemiological, immunological and molecular studies of leprosy.

Fátima da Conceição Silva

fconcei@ioc.fiocruz.br

CV

Parasitic diseases in humans and animals: immunology, diagnosis, clinical and treatment, with emphasis on those caused by parasites of the genus Leishmania; Mycoses in humans and animals: clinical, pathogenesis, immunology, diagnosis and treatment with emphasis on sporotrichosis; other fungal diseases;          Characterization and determination of the influence of the systemic and in situ immune response on the evolution of infectious and parasitic diseases of the cutaneous mucosal integument, skin immunity, in situ studies, inflammation, immunohistochemistry and murine models.

José Paulo Gagliardi Leite

jpgleite@ioc.fiocruz.br

CV

Detection and molecular characterization of viruses responsible for the etiology of acute gastroenteritis and development of diagnostic methodologies.

Joseli de Oliveira Ferreira

lila@ioc.fiocruz.br

CV

Study of the natural immunity to antigens candidates to compose an antimalarial vaccine, the genetic control of antiplasmodial specific immune response and immunopathology in human malaria in populations of Brazilian endemic areas.

Joseli Lannes Vieira

lannes@ioc.fiocruz.br

CV

Development of vaccines against parasitic infections; Immunopathogenesis and immunoregulation in parasitic infections.

Josué da Costa Lima Júnior

josue@ioc.fiocruz.br

CV

Development and evaluation of synthetic and recombinant antigens based on potentially vaccine proteins against malaria: Antigenicity, Immunogenicity and associations with the HLA of populations living in endemic areas.

Katia da Silva Calabrese

calabrese@ioc.fiocruz.br

CV

Research with protozoan parasites of macrophages in an experimental model including: immunology and therapeutics of leishmaniasis; pathology and immunology of Chagas' disease, emphasis on oral infection; ocular and intestinal toxoplasmosis.

Leonardo José Moura de Carvalho

leojmc@ioc.fiocruz.br

CV

Role of vascular dysfunction and inflammation in the pathogenesis and therapeutics of cerebral malaria, new drugs against hepatic and erythrocytic forms of Plasmodium falciparum and P. vivax, Vaccines against malaria.

Lilian Rose Pratt Riccio

riccio@ioc.fiocruz.br

CV

Study of the cellular and humoral immune responses against Plasmodium falciparum antigens and Plasmodium vivax canidatos the antimalarial vaccine in naturally exposed populations living in the Brazilian Amazon and evaluation of the role of human and parasite polymorphisms in the development of the specific immune response. In vitro evaluation of the resistance of Plasmodium falciparum and Plasmodium vivax isolates to antimalarial drugs and the evaluation of the antimalarial potential of new drugs of established or experimental use.

Luzia Maria de Oliveira

lpinto@ioc.fiocruz.br

CV

Mechanisms of deregulation of host immune response in Dengue infection, observing the involvement of components of the Complement System, Chemokines and proteins associated with coagulation and inflammation.

Marcelo Alves Pinto

marcelop@ioc.fiocruz.br

CV

Pathogenesis of acute viral hepatitis and non-human primate fulminants as models for the study of the pathogenesis of viral hepatitis study of hepatitis by hepatitis A virus, hepatitis E, HSV1 and 2, and parvovirus B19 Balb C mouse as an experimental model for herpetic encephalitis targeted for selection of new antiviral drugs and interference RNA therapy.

Maria de Fátima Ferreira da Cruz

mffcruz@ioc.fiocruz.br

CV

Malaria: Diagnosis, chemoresistance, gene polymorphism and immunopathology.

Mariza Gonçalves Morgado

mmorgado@ioc.fiocruz.br

CV

Our main interests concern: HIV diversity and its implications for progression to AIDS, epitopes of interest in vaccines, drug resistance and viral evolution. Immunopathology of HIV infection and HIV-Tuberculosis interaction.

Myrna Cristina Bonaldo

myrna.bonaldo@gmail.com

CV

Establishment of yellow fever vaccine virus as an expression platform for recombinant vaccines targeting human pathogens and understanding the structure and function of the viral genome.

Patricia de Azambuja Penna

azambuja.p@gmail.com

CV

Aspects of the interaction of triatomines with the parasite Trypanosoma cruzi, an etiological agent of Chagas' disease: in this line of research, the digestion physiology, intestinal microbiota, endocrinology and insect immunology, especially Rhodnius prolixus, are analyzed.

Roberta Olmo Pinheiro

rolmo@ioc.fiocruz.br

CV

IHost-pathogen interaction, cell death (apoptosis, pyroptose and autophagy), phagocytosis, immunoregulation, and inflammation. I have studied the immunopathogenic mechanisms related to the different clinical forms of leprosy, as well as to the reactional episodes of the disease. 

Vanessa Salete de Paula

vdepaula@ioc.fiocruz.br

CV

Viral hepatitis with emphasis on molecular epidemiology, genotyping, development and optimization of molecular diagnostic methods, serological and alternative methods of collection. It also works with herpes viruses, mainly with differential diagnosis, molecular epidemiology, co-infection with HIV and antiviral RNA interference therapy (RNAi).

Collaborator Faculty of the Program

Supervisor

E-mail

Curriculum

Area of Concentration

Research interests

Ana Gisele da Costa Neves Ferreira

anag@fiocruz.br

CV

Genética e Bioquímica

Molecular characterization of the natural resistance phenomenon of different animals to the toxic effects of snake venoms; Use of proteomic technology for the characterization of animal poisons and in the study of parasitic, infectious and neoplastic diseases

Flavia Lima Ribeiro Gomes

flavia.gomes@ioc.fiocruz.br

CV

Immunology and Pathogenesis

Role of the innate immune response in the immunopathogenesis of infectious diseases

Geraldo Moura Batista Pereira

gmbpereira@gmail.com 

CV

Imunologia e Patogenia

Mechanisms for regulating the human immune response to mycobacteria, and their applications in the control of leprosy and tuberculosis through vaccines and diagnostic tests. Current projects in modulating the immune response by regulatory T lymphocytes in the pathogenesis of leprosy

José Batista de Jesus

jbj@ioc.fiocruz.br

 

CV

Genética e Bioquímica

Biochemistry, expression and function of protozoan proteases and insect vectors of medical importance; Study of the biology of the interaction of protozoa with the host cell, using tools to analyze the genetic expression and cellular ultrastructure; Functional genomics of Culicidae vectors and protozoan of medical importance.

Juliana Helena da Silva Barros

juliana.barros@ioc.fiocruz.br

CV

Ecology and Epidemiology

Characterization of trypanosomatids by parasitological, biological and molecular methods. Diagnosis of the natural infection of trypanosomatids in mammalian hosts and vectors. Trypanosoma and Leishmania transmission cycles

Otacilio da Cruz Moreira

otacilio@ioc.fiocruz.br

CV

Genética e Bioquímica

Molecular diagnosis of infectious diseases parasitology and bioenergetics, developing methodologies for diagnosis and genotyping of parasitic protozoa, as well as the study of moplecular markers of virulence and pathogenesis in Chagas' disease and leishmaniasis.

Paulo Renato Rivas Totino

prtotino@ioc.fiocruz.br

CV

Biology

Immunopathogenesis of experimental and human malarial infections and; Biology of the programmed cell death in malaria parasites

Rafaela Vieira Bruno

rafaelav@ioc.fiocruz.br

CV

Genetics and Biochemistry

Characterization of genes that control biological rhythms in insect vectors.

Suzana Corte Real Faria

scrf@ioc.fiocruz.br

CV

Biologia

Estudo do perfil celular e molecular nas Leishmanioses humanas e canina e, nas infecções experimentais em camundongos. Analisando a participação de moléculas de superfície e a produção de citocinas e quimiocinas na interação de parasitos do gênero Leishmania com células residentes da derme e células inflamatória.

Tulio Machado Fumian

tuliomf@ioc.fiocruz.br

CV

Genetics and Biochemistry

Viral gastroenteritis with emphasis on molecular epidemiology, genotyping, development and optimization of methods for molecular diagnosis, especially norovirus. It also works with environmental virology, detecting and characterizing enteric viruses from different aquatic and food matrices.

 

 

 
Atualizado em 05/10/2018

 

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